概述

  • 产品名称Amyloid β肽(16-22)
  • 描述
    Amyloidogenic肽forming an antiparallel β-sheet. Amyloid β肽(16-22).
  • 生物学描述

    Amyloidogenic peptide forming an antiparallel β-sheet. A 7 residue section of the parent β-peptide (42 residues) from Alzheimer's amyloid precursor protein. Comprises the central hydrophobic core thought to be important in amyloid β formation. Region contains four Alzheimer's disease causing mutation sites.

  • 纯度> 95%

性能

  • 化学名称KLVFFAE
  • 分子量853.03
  • 化学结构Chemical Structure
  • 分子式C43H65N8O10
  • 存放说明Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • 溶解度概述Soluble in water to 1 mg/ml
  • 处理

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 来源

    Synthetic

  • 研究领域

    Amyloid β peptide (16-22) (ab120825)参考文献

    This product has been referenced in:
    • Santini S  et al. Pathway complexity of Alzheimer's beta-amyloid Abeta16-22 peptide assembly. Structure 12:1245-55 (2004). Read more (PubMed: 15242601) »
    • Favrin G  et al. Oligomerization of amyloid Abeta16-22 peptides using hydrogen bonds and hydrophobicity forces. Biophys J 87:3657-64 (2004). Read more (PubMed: 15377534) »
    • Ma B & Nussinov R Stabilities and conformations of Alzheimer's beta -amyloid peptide oligomers (Abeta 16-22, Abeta 16-35, and Abeta 10-35): Sequence effects. Proc Natl Acad Sci U S A 99:14126-31 (2002). Read more (PubMed: 12391326) »

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