Amyloid β肽(1-43) (Aβ43) (ab120963)

概述

  • 产品名称Amyloid β肽(1-43) (Aβ43)
  • 描述
    Highly toxic, amyloidogenic amyloid β (1-43)肽fragment
  • 生物学描述

    Amyloid β peptide fragment. Highly toxic, showing higher neurotoxicity compared to Aβ40 and Aβ42 (ab120479 / ab120301). Aggregates and is potently amyloidogenic in vivo. Induces synaptic dysfunction and impairs memory.

  • 纯度> 95%

性能

    Amyloid β Peptide (1-43) (Aβ43) (ab120963)参考文献

    This product has been referenced in:
    • Saito T  et al. Potent amyloidogenicity and pathogenicity of Aß43. Nat Neurosci 14:1023-32 (2011). Read more (PubMed: 21725313) »
    • Jarrett JT  et al. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 32:4693-7 (1993). Read more (PubMed: 8490014) »
    • Hilbich C  et al. Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4. Eur J Biochem 201:61-9 (1991). Read more (PubMed: 1915378) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120963.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"