小鼠单克隆抗体[R10/99] to Amylin
Mouse, Rat, Rabbit, Guinea pig, Cat, Dog, Chinese hamster
, corresponding to amino acids 40-50 of Human Amylin coupled to tuberculin.
Human Pancreas, Islet of Langerhans
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
Preservative: 0.09% Sodium azide
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration.
1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Belongs to the calcitonin family.
The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
Amyloid fibrils are degraded by IDE.
Information by UniProt
Diabetes associated peptide antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Amylin antibody [R10/99] (ab115766)
ab115766, at 1/100 staining Amylin in formalin fixed,
paraffin embedded Human Pancreas, Islet of
Langerhans by Immunohistochemistry. Developed using biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase streptavidin and chromogen.
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