概述

  • 产品名称Anti-Amylin抗体
    参阅全部 Amylin 一抗
  • 描述
    兔多克隆抗体to Amylin
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit, Cat, Dog, Baboon
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Amylin.

  • 阳性对照
    • This antibody gave a positive signal in a human pancreas tissue section.

性能

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应用

Our Abpromise guarantee covers the use of ab77387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
  • 序列相似性Belongs to the calcitonin family.
  • 结构域The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
  • 翻译后修饰Amyloid fibrils are degraded by IDE.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amylin antibody
    • DAP antibody
    • Diabetes associated peptide antibody
    • Diabetes-associated peptide antibody
    • IAP antibody
    • IAPP antibody
    • IAPP_HUMAN antibody
    • Insulinoma amyloid peptide antibody
    • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
    • Islet amyloid polypeptide antibody
    see all

Anti-Amylin antibody 图像

  • IHC image of Amylin staining in Human Pancreas section, performed on a BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab77387, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX

Anti-Amylin antibody (ab77387)参考文献

ab77387 has not yet been referenced specifically in any publications.

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