概述

  • 产品名称
  • 描述
    兔多克隆抗体to Amylin
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (N terminal).

  • 阳性对照
    • Pancreas.

性能

应用

Our Abpromise guarantee covers the use of ab15125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: 1/200 for 10 min at RT. Boil tissue sections in 10mM
    citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min before commencing with IHC staining protocol.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
    • 序列相似性
      Belongs to the calcitonin family.
    • 结构域
      The mature protein is largely unstructured in the absence of a cognate ligand, and has a strong tendency to form fibrillar aggregates. Homodimerization may be the first step of amyloid formation.
    • 翻译后修饰
      Amyloid fibrils are degraded by IDE.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Amylin antibody
      • DAP antibody
      • Diabetes associated peptide antibody
      • Diabetes-associated peptide antibody
      • IAP antibody
      • IAPP antibody
      • IAPP_HUMAN antibody
      • Insulinoma amyloid peptide antibody
      • Islet amyloid polypeptide (diabetes associated peptide; amylin) antibody
      • Islet amyloid polypeptide antibody
      see all

    图片

    • ab15125 staining Amylin in human pancreas by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    文献

    This product has been referenced in:
    • Suzuki H & Yamamoto T Amylin-like immunoreactivity in pancreatic X cells of the black-spotted frog Rana (Pelophylax) nigromaculata. Tissue Cell 46:535-9 (2014). IHC-Fr ; Frog . Read more (PubMed: 25458814) »

    See 1 Publication for this product

    客户评价及客户问答

    Thank you for your enquiry and your interest in our products.
    Concerning ab18018 - there is significant sequence homology between human amylin and that of mouse and rat, but this antibody has only been tested with human samples.
    Unfortunately...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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