Anti-Aminoacylase 1抗体(ab96098)

概述

  • 产品名称Anti-Aminoacylase 1抗体
    参阅全部 Aminoacylase 1 一抗
  • 描述
    兔多克隆抗体to Aminoacylase 1
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 89 and 336 of Human Aminoacylase 1 (NP_000657).

  • 阳性对照
    • 293T, A431, HeLa, HepG2, MOLT4, H1299 and Raji cell lysates ICC/IF: A431 cell

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab96098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 46 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
  • 组织特异性Expression is highest in kidney, strong in brain and weaker in placenta and spleen.
  • 疾病相关Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D) [MIM:609924]. ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.
  • 序列相似性Belongs to the peptidase M20A family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACY 1 antibody
    • ACY-1 antibody
    • Acy1 antibody
    • ACY1_HUMAN antibody
    • ACY1D antibody
    • ACYLASE antibody
    • Acylase I antibody
    • Aminoacylase-1 antibody
    • EC 3.5.1.14 antibody
    • epididymis secretory protein Li 5 antibody
    • HEL-S-5 antibody
    • N acyl L amino acid amidohydrolase antibody
    • N-acyl-L-amino-acid amidohydrolase antibody
    • OTTHUMP00000212459 antibody
    • OTTHUMP00000212462 antibody
    • OTTHUMP00000212463 antibody
    • OTTHUMP00000212464 antibody
    • OTTHUMP00000212465 antibody
    see all

Anti-Aminoacylase 1 antibody 图像

  • Anti-Aminoacylase 1 antibody (ab96098) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 46 kDa
  • Immunofluorescence analysis of Aminoacylase 1 in paraformaldehyde fixed A431, using ab96098 at a 1/200 dilution. Lower image merged with DNA probe.

Anti-Aminoacylase 1 antibody (ab96098)参考文献

ab96098 has not yet been referenced specifically in any publications.

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