概述

  • 产品名称Anti-AMID抗体
    参阅全部 AMID 一抗
  • 描述
    山羊多克隆抗体to AMID
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    GSQVSVESGALHC

    , corresponding to N terminal amino acids 2-13 of Human AMID.

  • 阳性对照
    • Human Heart and Skeletal Muscle tissues

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115456 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/128000.
IHC-P Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.
  • 组织特异性Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells.
  • 序列相似性Belongs to the FAD-dependent oxidoreductase family.
  • 细胞定位Cytoplasm. Mitochondrion outer membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5430437E11Rik antibody
    • aifm2 antibody
    • AIFM2_HUMAN antibody
    • AMID antibody
    • Apoptosis inducing factor (AIF) homologous mitochondrion associated inducer of death antibody
    • Apoptosis inducing factor (AIF) like mitochondrion associated inducer of death antibody
    • Apoptosis inducing factor mitochondrion associated 2 antibody
    • Apoptosis-inducing factor 2 antibody
    • Apoptosis-inducing factor homologous mitochondrion-associated inducer of death antibody
    • Apoptosis-inducing factor-like mitochondrion-associated inducer of death antibody
    • Cys51Stop antibody
    • HGNC11998 antibody
    • p53 responsive gene 3 antibody
    • p53 tumor suppressor antibody
    • p53-responsive gene 3 protein antibody
    • PRG3 antibody
    • TRP53 antibody
    • Tumor protein p53 antibody
    see all

Anti-AMID antibody 图像

  • ab115456, at 4 µg/ml, staining AMID in formalin-fixed, paraffin-embedded Human Heart tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • ab115456, at 4 µg/ml, staining AMID in formalin-fixed, paraffin-embedded Human Skeletal Muscle tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-AMID antibody (ab115456)参考文献

ab115456 has not yet been referenced specifically in any publications.

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