概述

  • 产品名称Anti-AMHR2抗体
    参阅全部 AMHR2 一抗
  • 描述
    兔多克隆抗体to AMHR2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 12-61 of Mouse AMHR2 (NP_653130.2)

  • 阳性对照
    • Mouse brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 61 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
  • 疾病相关Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS2) [MIM:261550]. PMDS2 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AMH type II receptor antibody
    • AMHR antibody
    • AMHR2 antibody
    • AMHR2_HUMAN antibody
    • Anti Mullerian hormone receptor, type II antibody
    • Anti-Muellerian hormone type II receptor antibody
    • Anti-Muellerian hormone type-2 receptor antibody
    • MGC141312 antibody
    • MIS type II receptor antibody
    • MISR2 antibody
    • MISRII antibody
    • MRII antibody
    • Muellerian hormone type 2 receptor antibody
    • Muellerian hormone type II receptor antibody
    • Muellerian inhibiting substance type II receptor antibody
    • Mullerian hormone receptor type II antibody
    • Mullerian inhibiting substance type II receptor antibody
    see all

Anti-AMHR2 antibody 图像

  • Anti-AMHR2 antibody (ab118694) at 1 µg/ml + Mouse brain lysate at 10 µg

    Predicted band size : 61 kDa

Anti-AMHR2 antibody (ab118694)参考文献

ab118694 has not yet been referenced specifically in any publications.

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