概述

  • 产品名称
  • 描述
    兔多克隆抗体to AMH
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 430-460 of Human AMH

  • 阳性对照
    • 293 cell lysate; Mouse liver tissue lysate; Prostate carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab103233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 60 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性
    Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
  • 细胞定位
    Secreted
  • 数据库链接
  • 别名
    • Anti muellerian hormone antibody
    • MIF antibody
    • MIS antibody
    • Muellerian inhibiting factor antibody
    • Mullerian inhibiting substance antibody
    see all

图片

  • Anti-AMH antibody (ab103233) at 1/100 dilution + 293 cell lysate at 35 µg

    Predicted band size: 60 kDa

  • Anti-AMH antibody (ab103233) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size: 60 kDa

  • ab103233, at 1/50 dilution, staining AMH in formalin-fixed, paraffin-embedded prostate carcinoma by Immunohistochemistry using a peroxidase conjugated secondary antibody and DAB staining.

文献

This product has been referenced in:
  • Del Valle I  et al. A genomic atlas of human adrenal and gonad development. Wellcome Open Res 2:25 (2017). IHC ; Human . Read more (PubMed: 28459107) »
  • Wang W  et al. Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration. Cell Death Dis 3:e433 (2012). WB . Read more (PubMed: 23190605) »

See all 2 Publications for this product

客户评价及客户问答

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Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (HeLa)
Permeabilization
No
Specification
HeLa
Fixative
Methanol
Username

Dr. Kirk Mcmanus

Verified customer

提交于 Sep 29 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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