概述

  • 产品名称Anti-AMH抗体[5/6]
    参阅全部 AMH 一抗
  • 描述
    小鼠单克隆抗体[5/6] to AMH
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Sheep, Human, Baboon
    预测可用于: Rat, Cow, Pig
  • 免疫原

    Synthetic peptide:

    VPTAYAGKLLISLSEERISAHHVPNMVATEC

    , corresponding to C terminal amino acids 527-557 of Human AMH.

  • 阳性对照
    • Mouse ovary tissue.

性能

应用

Our Abpromise guarantee covers the use of ab24542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/20 - 1/40. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Sodium Citrate buffer pH 6.0 is recommended for this purpose.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
    • 细胞定位Secreted
    • 数据库链接
    • 别名
      • Anti muellerian hormone antibody
      • MIF antibody
      • MIS antibody
      • Muellerian inhibiting factor antibody
      • Mullerian inhibiting substance antibody
      see all

    Anti-AMH antibody [5/6] 图像

    • Ab24542, at a dilution of 1/20 to 1/40, staining formalin fixed paraffin embedded ovary tissue from a 25 day old mouse by Immunohystochemistry.

    Anti-AMH antibody [5/6] (ab24542)参考文献

    This product has been referenced in:
    • Kevenaar ME  et al. Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice. Endocrinology 147:3228-34 (2006). Read more (PubMed: 16556768) »
    • Weenen C  et al. Anti-Müllerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment. Mol Hum Reprod 10:77-83 (2004). Read more (PubMed: 14742691) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"