概述

  • 产品名称Anti-AMFR抗体
    参阅全部 AMFR 一抗
  • 描述
    兔多克隆抗体to AMFR
  • 特异性ab76841 reacts specifically with the 73 kda (isoform 2) protein.
  • 经测试应用适用于: WB, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from the C terminal domain of human AMFR protein.

性能

应用

Our Abpromise guarantee covers the use of ab76841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/1000. Predicted molecular weight: 73 kDa.
IHC-P 1/50 - 1/200.
IHC-Fr 1/50 - 1/200.

靶标

  • 功能E3 ubiquitin-protein ligase which can target both itself and other proteins including CD3D and APOB for proteasomal degradation. Mediates polyubiquitination of CYP3A4. Specific receptor for the autocrine motility factor. Mediates tumor invasion and metastasis. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Promotes ubiquitination of misfolded proteins such as mutant CFTR; proposed to mediate sequential ubiquitination by recognizing already ubiquitin-conjugated substrates and to cooperate with E3 ubiquitin-protein ligase RNF5.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 CUE domain.
    Contains 1 RING-type zinc finger.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AMF receptor antibody
    • AMF receptor isoform 1 antibody
    • AMF receptor isoform 2 antibody
    • AMFR antibody
    • AMFR2_HUMAN antibody
    • Autocrine motility factor receptor antibody
    • Autocrine motility factor receptor precursor, isoform 1 antibody
    • Autocrine motility factor receptor precursor, isoform 2 antibody
    • E3 ubiquitin-protein ligase AMFR antibody
    • gp78 antibody
    • isoform 2 antibody
    • RING finger protein 45 antibody
    • RNF 45 antibody
    • RNF45 antibody
    see all

Anti-AMFR antibody (ab76841)参考文献

ab76841 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"