概述

  • 产品名称Anti-AMBRA1抗体
    参阅全部 AMBRA1 一抗
  • 描述
    兔多克隆抗体to AMBRA1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Chicken, Cow, Human
  • 免疫原

    A portion of amino acids 1-50 of human Ambra1.

  • 阳性对照
    • Human brain lysate

性能

应用

Our Abpromise guarantee covers the use of ab72098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 130 kDa (predicted molecular weight: 143 kDa).

靶标

  • 功能Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
  • 序列相似性Contains 3 WD repeats.
  • 细胞定位Cytoplasmic vesicle > autophagosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activating molecule in beclin 1 regulated autophagy antibody
    • Activating molecule in BECN1 regulated autophagy protein 1 antibody
    • Activating molecule in BECN1-regulated autophagy protein 1 antibody
    • Ambra1 antibody
    • AMRA1_HUMAN antibody
    • FLJ20294 antibody
    • Hypothetical protein FLJ20294 antibody
    • Hypothetical protein LOC55626 antibody
    • KIAA1736 antibody
    • MGC33725 antibody
    • WDR94 antibody
    see all

Anti-AMBRA1 antibody 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human small intestine tissue labelling AMBRA1 with ab72098 at 10µg/ml. Staining was enhanced by boiling tissue sections in 10mM sodium citrate buffer, pH6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes.

  • All lanes : Anti-AMBRA1 antibody (ab72098) at 1 µg/ml

    Lane 1 : human brain lysate
    Lane 2 : human brain lysate with immunizing peptide


    Predicted band size : 143 kDa
    Observed band size : 143 kDa

Anti-AMBRA1 antibody (ab72098)参考文献

This product has been referenced in:
  • Choubey V  et al. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy 10:1105-19 (2014). Rat . Read more (PubMed: 24879156) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"