Anti-Alx1抗体[3329D3a] (ab70604)

概述

  • 产品名称Anti-Alx1抗体[3329D3a]
    参阅全部 Alx1 一抗
  • 描述
    小鼠单克隆抗体[3329D3a] to Alx1
  • 经测试应用适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment derived from internal sequence of human Alx1

  • 阳性对照
    • Recombinant human Alx1.

性能

应用

Our Abpromise guarantee covers the use of ab70604 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 37 kDa.
Dot blot Use at an assay dependent dilution.

靶标

  • 功能Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development.
  • 组织特异性Cartilage and cervix tissue.
  • 疾病相关Defects in ALX1 are the cause of frontonasal dysplasia type 3 (FND3) [MIM:613456]. The term frontonasal dysplasia describes an array of abnormalities affecting the eyes, forehead and nose and linked to midfacial dysraphia. The clinical picture is highly variable. Major findings include true ocular hypertelorism; broadening of the nasal root; median facial cleft affecting the nose and/or upper lip and palate; unilateral or bilateral clefting of the alae nasi; lack of formation of the nasal tip; anterior cranium bifidum occultum; a V-shaped or widow's peak frontal hairline.
  • 序列相似性Belongs to the paired homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 翻译后修饰Acetylated at Lys-131 by EP300, leading to increased interaction with EP300 and enhances transcriptional activation activity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ALX homeobox 1 antibody
    • ALX homeobox protein 1 antibody
    • ALX1 antibody
    • ALX1_HUMAN antibody
    • CART 1 antibody
    • CART-1 antibody
    • CART1 antibody
    • Cartilage homeoprotein 1 antibody
    • Cartilage paired class homeoprotein 1 antibody
    • FND3 antibody
    see all

Anti-Alx1 antibody [3329D3a] 图像

  • Anti-Alx1 antibody [3329D3a] (ab70604) + immunising recombinant protein

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

Anti-Alx1 antibody [3329D3a] (ab70604)参考文献

ab70604 has not yet been referenced specifically in any publications.

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