参阅全部 ALS2CR2 一抗
- 特异性This is expected to recognise both human isoforms: ILPIP alpha (NP_061041) and ILPIP beta (AAF71042).
IHC-P, WBmore details
CDFPDEKDSYWEF , corresponding to amino acids 406-418 of Human ALS2CR2.
- Human heart or liver lysate.
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
- 纯度Immunogen affinity purified
- 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
||Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 47 kDa).Can be blocked with Human ALS2CR2 peptide (ab22984).
- 功能Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.
- 组织特异性Highly expressed in heart, skeletal muscle, testis, liver and colon.
- 序列相似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 protein kinase domain.
- 结构域The protein kinase domain is predicted to be catalytically inactive.
- 细胞定位Nucleus. Cytoplasm.
Information by UniProt
- ALS2 chromosome region gene 2 antibody
- ALS2CR2 antibody
- Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2 antibody
Anti-ALS2CR2 antibody 图像
Western blot - ALS2CR2 antibody (ab4122)
Predicted band size : 47 kDa
ab4122 at a concentration of 1µg/ml staining ALS2CR2 in human heart lysate (RIPA buffer, 30µg total protein per lane) by Western blot. Primary incubated for 1 hour and detected by chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ALS2CR2 antibody (ab4122)
ab4122 (3.8 µg/ml) staining ALS2CR2 in myocardial fibers in a transverse section of paraffin-embedded human heart following steamed antigen retrieval with citrate buffer pH6.
Anti-ALS2CR2 antibody (ab4122)参考文献
has not yet been referenced specifically in any publications.
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