Anti-alpha+beta SNAP抗体[6B7-3] (ab69742)

概述

  • 产品名称Anti-alpha+beta SNAP抗体[6B7-3]
    参阅全部 alpha+beta SNAP 一抗
  • 描述
    小鼠单克隆抗体[6B7-3] to alpha+beta SNAP
  • 特异性This antibody detects a doublet of 35 and 36 kDa proteins, corresponding to the apparent molecular mass of alpha + beta SNAP.
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Hamster, Cow, Dog, Human
  • 免疫原

    Recombinant full length bovine alpha SNAP protein expressed in E coli

  • 阳性对照
    • Rat brain tissue extract and mouse brain tissue extract.

性能

应用

Our Abpromise guarantee covers the use of ab69742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.5 µg/ml. Predicted molecular weight: 38 kDa.
IP Use at an assay dependent dilution.

靶标

  • 相关性Alpha, beta and gamma SNAPs, also known as soluble NSF attachment proteins, have apparent molecular weights on SDS PAGE of 35, 36 and 39 kDa, respectively. SNAP proteins mediate the association of NSF to membranes during vesicle fusion reaction, and play a prominent role in synaptic vesicle fusion. In addition, beta SNAP interacts with synaptotagmin and may be involved in calcium regulated exocytosis. SNAP was identified as being required for vesicle fusion in intra Golgi transport reaction in vitro. Alpha SNAP mediates the association of NSF to membranes during vesicle fusion reaction, and plays a prominent role and in synaptic vesicle fusion. Together with synaptotagmin and NSF, alpha SNAP modulates the interaction of SNAP25, VAMP, and syntaxin in, an ATP dependent manner, to form a complex with a sedimentation coefficient of 20 S. This complex may represent an intermediate involved in synaptic vesicle docking and fusion.
  • 细胞定位Cytoplasmic peripheral membrane protein.
  • 数据库链接
  • 别名
    • Alpha soluble NSF attachment protein antibody
    • Beta soluble NSF attachment protein antibody
    • N ethylmaleimide sensitive factor attachment protein alpha antibody
    • N ethylmaleimide sensitive factor attachment protein beta antibody
    • NAPA antibody
    • NAPB antibody
    • SNAP Alpha antibody
    • SNAP Beta antibody
    • SNAPA antibody
    • SNAPB antibody
    • SNARE antibody
    • Soluble NSF attachment protein antibody
    see all

Anti-alpha+beta SNAP antibody [6B7-3] (ab69742)参考文献

ab69742 has not yet been referenced specifically in any publications.

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