Anti-alpha Sarcoglycan抗体(ab92522)


  • 产品名称Anti-alpha Sarcoglycan抗体
    参阅全部 alpha Sarcoglycan 一抗
  • 描述
    兔多克隆抗体to alpha Sarcoglycan
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human alpha Sarcoglycan.

  • 阳性对照
    • Jurkat, HepG2 and HeLa cell extracts.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab92522 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab92522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 43 kDa.


  • 功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • 组织特异性Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.
  • 疾病相关Defects in SGCA are the cause of limb-girdle muscular dystrophy type 2D (LGMD2D) [MIM:608099]; also known as Duchenne-like muscular dystrophy autosomal recessive type 2 or severe childhood autosomal recessive muscular dystrophy (SCARMD). LGMD2D is an autosomal recessive degenerative myopathy characterized by progressive muscle wasting from early childhood with loss of independent ambulation by teenage years. Muscle biopsy shows necrosis, decreased immunostaining for alpha sarcoglycan, and adhalin deficiency. The phenotype is less severe than LGMD2C.
  • 序列相似性Belongs to the sarcoglycan alpha/epsilon family.
  • 细胞定位Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 50 DAG antibody
    • 50 kDa dystrophin associated glycoprotein antibody
    • 50 kDa dystrophin-associated glycoprotein antibody
    • 50DAG antibody
    • 50kD DAG antibody
    • 59kDa antibody
    • A2 antibody
    • adhalin antibody
    • ADL antibody
    • Alpha SG antibody
    • Alpha-sarcoglycan antibody
    • Alpha-SG antibody
    • Asg antibody
    • DAG2 antibody
    • DMDA2 antibody
    • Dystroglycan 2 antibody
    • Dystroglycan-2 antibody
    • LGMD2D antibody
    • sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody
    • SCARMD1 antibody
    • Sgca antibody
    • SGCA_HUMAN antibody
    see all

Anti-alpha Sarcoglycan antibody 图像

  • All lanes : Anti-alpha Sarcoglycan antibody (ab92522) at 1/500 dilution

    Lane 1 : Jurkat cell extracts
    Lane 2 : HepG2 cell extracts
    Lane 3 : HeLa cell extracts
    Lane 4 : HeLa cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 43 kDa

Anti-alpha Sarcoglycan antibody (ab92522)参考文献

ab92522 has not yet been referenced specifically in any publications.

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