概述

  • 产品名称Anti-alpha MSH抗体
    参阅全部 alpha MSH 一抗
  • 描述
    兔多克隆抗体to alpha MSH
  • 特异性Anti-a-MSH cross-reacts with des-Ac-a-MSH and [Val-OH13]-a-MSH. Minimal cross-reactivity is observed with human ACTH (1-39) and ACTH (1-24).
  • 经测试应用适用于: RIAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic human MSH alpha peptide conjugated to bovine serum albumin. The mid-region sequence of MSH alpha (amino acids 4-10) is identical to the ACTH and MSH beta sequences and highly conserved in the MSH gamma sequence.

  • 常规说明Affinity constant Ka: at least 1x109 L/M

性能

应用

Our Abpromise guarantee covers the use of ab50013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
RIA
  • 应用说明RIA: 1/3000 (2nd antibody and polyethylene glycol method) using 5-7pg of 125I-a-MSH.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Melanocyte-stimulating hormone belongs to a group called the melanocortins. This group includes ACTH, alpha-MSH, beta-MSH and gamma-MSH; these peptides are all cleavage products of a large precursor peptide called pro-opiomelanocortin (POMC). Alpha-MSH is the most important melanocortin for pigmentation. It increases the pigmentation of skin by increasing melanin production in melanocytes.
    • 细胞定位Secreted
    • 数据库链接
    • 别名
      • Alpha MSH antibody
      • Melanotropin alpha antibody
      • POMC antibody
      • proopiomelanocortin antibody

    Anti-alpha MSH antibody (ab50013)参考文献

    ab50013 has not yet been referenced specifically in any publications.

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