Anti-alpha Internexin抗体(ab24523)

概述

  • 产品名称Anti-alpha Internexin抗体
    参阅全部 alpha Internexin 一抗
  • 描述
    鸡多克隆抗体to alpha Internexin
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Cat, Human
  • 免疫原

    Recombinant full length protein expressed in E. coli.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 10mM Sodium Azide.
  • Concentration information loading...
  • 纯化说明This antibody was purified from egg yolk by chloroform delipidation followed by PEG precipitation.
  • 克隆多克隆
  • 同种型IgY
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab24523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC/IF
  • 应用说明IF: 1/1000 and higher.
    WB: 1/10000 and higher. Detects a band of approximately 66-68 kDa (the human protein runs at ~68 kDa, while rat, mouse and other species run at ~66 kDa). Minor bands at ~150 kDa are probably covalent dimers, and bands at ~50 kDa represent alpha internexin breakdown products. (Predicted molecular weight: 55 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
    • 组织特异性Found predominantly in adult CNS.
    • 序列相似性Belongs to the intermediate filament family.
    • 发展阶段Expressed in brain as early as the 16th week of gestation, and increased rapidly and reached a steady state level by the 18th week of gestation.
    • 翻译后修饰O-glycosylated.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 66 kDa neurofilament protein antibody
      • AINX_HUMAN antibody
      • Alpha Inx antibody
      • Alpha-internexin antibody
      • Alpha-Inx antibody
      • INA antibody
      • Internexin neuronal intermediate filament protein alpha antibody
      • MGC12702 antibody
      • NEF 5 antibody
      • NEF5 antibody
      • Neurofilament 5 (66kD) antibody
      • Neurofilament 5 antibody
      • Neurofilament 66 antibody
      • Neurofilament 66 tax binding protein antibody
      • Neurofilament-66 antibody
      • NF 66 antibody
      • NF-66 antibody
      • NF66 antibody
      • TXBP 1 antibody
      • TXBP1 antibody
      see all

    Anti-alpha Internexin antibody (ab24523)参考文献

    ab24523 has not yet been referenced specifically in any publications.

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