Anti-alpha Defensin 5抗体[8C8] (ab90802)
Key features and details
- Mouse monoclonal [8C8] to alpha Defensin 5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-alpha Defensin 5抗体[8C8]
参阅全部 alpha Defensin 5 一抗 -
描述
小鼠单克隆抗体[8C8] to alpha Defensin 5 -
宿主
Mouse -
特异性
ab90802 recognizes the propeptide and the partially processed forms (aa 36-94 and 56-94), but it hardly recognizes mature peptide. No cross reactivity with HD6, lysozyme, or sPLA2 has be detected. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Chimpanzee -
免疫原
Recombinant fragment corresponding to Human alpha Defensin 5 aa 20-94.
Sequence:ESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRT GRCATRESLSGVCEISGRLYRLCCR
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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纯度
Protein A purified -
纯化说明
ab90802 was filtered through a 0.2 µm filter. -
克隆
单克隆 -
克隆编号
8C8 -
同种型
IgG2b -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab90802于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P | (2) |
1/50.
|
说明 |
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IHC-P
1/50. |
靶标
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功能
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. -
组织特异性
Paneth cells of the small intestine (at protein level). -
序列相似性
Belongs to the alpha-defensin family. -
翻译后修饰
Glycosylated. -
细胞定位
Secreted. Cytoplasmic vesicle > secretory vesicle. Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form. - Information by UniProt
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数据库链接
- Entrez Gene: 463972 Chimpanzee
- Entrez Gene: 1670 Human
- Omim: 600472 Human
- SwissProt: Q5G861 Chimpanzee
- SwissProt: Q01523 Human
- Unigene: 655233 Human
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别名
- alpha 5 antibody
- DEF5 antibody
- DEF5_HUMAN antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab90802 被引用在 2 文献中.
- Liszt KI et al. Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity. J Clin Invest 132:N/A (2022). PubMed: 34784295
- Spencer JD et al. Human alpha defensin 5 expression in the human kidney and urinary tract. PLoS One 7:e31712 (2012). IHC ; Human . PubMed: 22359618