Anti-alpha 2b Adrenergic Receptor抗体(ab91468)

概述

  • 产品名称Anti-alpha 2b Adrenergic Receptor抗体
    参阅全部 alpha 2b Adrenergic Receptor 一抗
  • 描述
    兔多克隆抗体to alpha 2b Adrenergic Receptor
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the center region of Human alpha 2b Adrenergic Receptor conjugated to KLH (NP_000673.2).

  • 阳性对照
    • MDA-MB231 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab91468 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 50 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha 2B adrenergic receptor subtype was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. Alpha 2B adrenergic receptor gene contains no introns in either its coding or untranslated sequences.
    • 细胞定位Cell Membrane
    • 数据库链接
    • 别名
      • ADRA2B antibody
      • ADRA2RL1 antibody
      • ADRARL1 antibody
      • Alpha 2 adrenergic receptor subtype C2 antibody
      • Alpha 2B adrenoceptor antibody
      • Alpha 2B adrenoreceptor antibody
      • alpha 2BAR antibody
      • ALPHA2BAR antibody
      see all

    Anti-alpha 2b Adrenergic Receptor antibody 图像

    • Anti-alpha 2b Adrenergic Receptor antibody (ab91468) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

      Predicted band size : 50 kDa

    Anti-alpha 2b Adrenergic Receptor antibody (ab91468)参考文献

    ab91468 has not yet been referenced specifically in any publications.

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