Anti-alpha 2 Macroglobulin抗体(HRP) (ab7339)

概述

  • 产品名称Anti-alpha 2 Macroglobulin抗体(HRP)
    参阅全部 alpha 2 Macroglobulin 一抗
  • 描述
    山羊多克隆抗体to alpha 2 Macroglobulin (HRP)
  • 偶联物HRP
  • 经测试应用适用于: Dot blot, ELISA, IHC-Fr, Immunomicroscopy, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Alpha-2-Macroglobulin [Human Plasma]

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液pH: 7.60
    Preservative: 0.01% Gentamicin sulphate
    Constituents: 0.88% Sodium chloride, 1% BSA, 0.42% Potassium phosphate
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab7339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot
ELISA
IHC-Fr
Immunomicroscopy
WB
  • 应用说明Immunoblotting (western or dot blot)
    ELISA (1:12,000 to 1:60,000)
    Immunoperoxidase electron microscopy
    Immunomicroscopy
    as well as other peroxidase-antibody based enzymatic assays.
  • 靶标

    • 功能Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
    • 组织特异性Secreted in plasma.
    • 序列相似性Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
    • 发展阶段Contrary to the rat protein, which is an acute phase protein, this protein is always present at high levels in circulation.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A2m antibody
      • A2MG_HUMAN antibody
      • Alpha 2 M antibody
      • Alpha 2M antibody
      • Alpha-2-M antibody
      • Alpha-2-macroglobulin antibody
      • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody
      • CPAMD5 antibody
      • DKFZp779B086 antibody
      • FWP007 antibody
      • S863 7 antibody
      see all

    Anti-alpha 2 Macroglobulin antibody (HRP) (ab7339)参考文献

    ab7339 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. As these 4 antibodies are all polyclonal antibodies, each will recognize multiple epitopes. If you have any more questions, please do contact us again.

    The experiments you are pursuing sound very interesting and we would like to help. We are about to implement a trial 'try risk free' scheme which says that if an antibody is purchased and used in an experiment outside that written on the datasheet, and...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"