Anti-alpha 2 Macroglobulin抗体(ab92840)

概述

性能

应用

Our Abpromise guarantee covers the use of ab92840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at a concentration of 5 µg/ml (for coating) or 0.2 µg/ml (for detection).
    WB: Use at a concentration of 0.2 µg/ml. Predicted molecular weight: 164 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
    • 组织特异性Secreted in plasma.
    • 序列相似性Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
    • 发展阶段Contrary to the rat protein, which is an acute phase protein, this protein is always present at high levels in circulation.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A2m antibody
      • A2MG_HUMAN antibody
      • Alpha 2 M antibody
      • Alpha 2M antibody
      • Alpha-2-M antibody
      • Alpha-2-macroglobulin antibody
      • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody
      • CPAMD5 antibody
      • DKFZp779B086 antibody
      • FWP007 antibody
      • S863 7 antibody
      see all

    Anti-alpha 2 Macroglobulin antibody (ab92840)参考文献

    ab92840 has not yet been referenced specifically in any publications.

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