Anti-alpha 2 Catenin抗体[EPR1795] (ab76015)

概述

• 产品名称
  Anti-alpha 2 Catenin抗体[EPR1795]
  参阅全部 alpha 2 Catenin 一抗
• 描述
  兔单克隆抗体[EPR1795] to alpha 2 Catenin
• 经测试应用
  适用于: WB, IP, ICCmore details
  不适用于: Flow Cyt or IHC-P
• 种属反应性
  与反应: Mouse, Rat, Human
  
• 免疫原

  A synthetic peptide corresponding to residues in human alpha 2 Catenin.

• 阳性对照
  • Mouse brain lysate.
• 常规说明

  This product is a recombinant rabbit monoclonal antibody.

  Produced using Abcam’s RabMAb^® technology. RabMAb^® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• 纯度
  Tissue culture supernatant
• 克隆
  单克隆
• 克隆编号
  EPR1795
• 同种型
  IgG
• 研究领域
  • Signal Transduction
  • Cytoskeleton / ECM
  • Cell Adhesion
  • Cadherins

  • Cancer
  • Invasion/microenvironment
  • ECM
  • Cell adhesion
  • Cadherins

应用

靶标

• 功能
  May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation.
• 序列相似性
  Belongs to the vinculin/alpha-catenin family.
• 细胞定位
  Cytoplasm. Cytoplasm > cytoskeleton. Cell junction > adherens junction. Cell membrane. Cell projection > axon. Recruited to the nucleus upon ZNF639 overexpression.

• Target information above from: UniProt accession P26232 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 1496 Human
  • Entrez Gene: 12386 Mouse
  • Entrez Gene: 297357 Rat
  • Omim: 114025 Human
  • SwissProt: P26232 Human
  • SwissProt: Q61301 Mouse
  • Unigene: 167368 Human
  • Unigene: 34637 Mouse
• 别名
  • Alpha catenin related protein antibody
  • Alpha N catenin antibody
  • Alpha N-catenin antibody

  • Alpha-catenin-related protein antibody
  • Cadherin associated protein related antibody
  • Cancer/testis antigen 114 antibody
  • CAP R antibody
  • CAPR antibody
  • Catenin (cadherin associated protein) alpha 2 antibody
  • Catenin alpha 2 antibody
  • Catenin alpha-2 antibody
  • CT114 antibody
  • CTNA2_HUMAN antibody
  • CTNN A2 antibody
  • CTNNA 2 antibody
  • CTNNA2 antibody
  • CTNR antibody
  • DKFZp686H02198 antibody

  see all

实验方案

• Western blot protocols
• Immunoprecipitation protocols
• Immunocytochemistry & immunofluorescence protocols