Anti-alpha 1b Adrenergic Receptor抗体(ab15851)

概述

• 产品名称
  Anti-alpha 1b Adrenergic Receptor抗体
  参阅全部 alpha 1b Adrenergic Receptor 一抗
• 描述
  鸡多克隆抗体to alpha 1b Adrenergic Receptor
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  Synthetic peptide, corresponding to amino acids 200-299 of Human alpha 1b Adrenergic Receptor.

• 阳性对照
  • Testing antigen control, Pooled pre-immune background control.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  Preservative: None
  Constituents: PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 克隆
  多克隆
• 同种型
  IgY
• 研究领域
  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • GPCR
  • Adrenergic Receptors

应用

靶标

• 功能
  This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
• 序列相似性
  Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily.
• 细胞定位
  Nucleus membrane. Cell membrane. Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.

• Target information above from: UniProt accession P35368 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 147 Human
  • Omim: 104220 Human
  • SwissProt: P35368 Human
  • Unigene: 368632 Human
• 别名
  • ADA1B_HUMAN antibody
  • ADRA 1 antibody
  • Adra 1b antibody

  • ADRA1 antibody
  • ADRA1B antibody
  • Adrenergic alpha 1B receptor antibody
  • Adrenergic receptor alpha 1b antibody
  • Adrenoceptor alpha 1B antibody
  • Alpha 1 adrenergic receptor antibody
  • Alpha 1B adrenoceptor antibody
  • Alpha 1B adrenoreceptor antibody
  • Alpha-1B adrenergic receptor antibody
  • Alpha-1B adrenoceptor antibody
  • Alpha-1B adrenoreceptor antibody
  • Alpha1 adrenergic receptor antibody
  • Alpha1B adrenergic receptor antibody
  • Alpha1BAR antibody

  see all

实验方案

• Western blot protocols