Anti-alpha 1b Adrenergic Receptor抗体(ab15851)

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概述

  • 产品名称
    Anti-alpha 1b Adrenergic Receptor抗体
    参阅全部 alpha 1b Adrenergic Receptor 一抗
  • 描述
    鸡多克隆抗体to alpha 1b Adrenergic Receptor
  • 宿主
    Chicken
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 200-299 of Human alpha 1b Adrenergic Receptor.

  • 阳性对照
    • Testing antigen control, Pooled pre-immune background control.

性能

应用

Our Abpromise guarantee covers the use of ab15851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Predicted molecular weight: 62.4 kDa.

靶标

  • 功能
    This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily.
  • 细胞定位
    Nucleus membrane. Cell membrane. Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
  • Information by UniProt
  • 数据库链接
    • 别名
      • ADA1B_HUMAN antibody
      • ADRA 1 antibody
      • Adra 1b antibody
      • ADRA1 antibody
      • ADRA1B antibody
      • Adrenergic alpha 1B receptor antibody
      • Adrenergic receptor alpha 1b antibody
      • Adrenoceptor alpha 1B antibody
      • Alpha 1 adrenergic receptor antibody
      • Alpha 1B adrenoceptor antibody
      • Alpha 1B adrenoreceptor antibody
      • Alpha-1B adrenergic receptor antibody
      • Alpha-1B adrenoceptor antibody
      • Alpha-1B adrenoreceptor antibody
      • Alpha1 adrenergic receptor antibody
      • Alpha1B adrenergic receptor antibody
      • Alpha1BAR antibody
      see all

    实验方案

    文献

    This product has been referenced in:
    • Jensen BC  et al. Ten commercial antibodies for alpha-1-adrenergic receptor subtypes are nonspecific. Naunyn Schmiedebergs Arch Pharmacol 379:409-12 (2009). WB ; Mouse . Read more (PubMed: 18989658) »

    See 1 Publication for this product

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