Anti-alpha 1 Sodium Potassium ATPase (phospho Y10)抗体[EPR2375(2)] (ab124677)


  • 产品名称Anti-alpha 1 Sodium Potassium ATPase (phospho Y10)抗体[EPR2375(2)]
    参阅全部 alpha 1 Sodium Potassium ATPase 一抗
  • 描述
    兔单克隆抗体[EPR2375(2)] to alpha 1 Sodium Potassium ATPase (phospho Y10)
  • 特异性ab124677 only detects alpha 1 Sodium Potassium ATPase phosphorylated at Tyrosine 10.
  • 经测试应用适用于: WB, IPmore details
    不适用于: Flow Cyt,ICC or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A phospho specific peptide corresponding to residues surrounding Tyrosine 10 of Human alpha 1 Sodium Potassium ATPase.

  • 阳性对照
    • HeLa cell lysate, treated with Pervanadate.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.



Our Abpromise guarantee covers the use of ab124677 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Detects a band of approximately 100 kDa (predicted molecular weight: 113 kDa).
IP 1/10 - 1/100.
  • 应用说明Is unsuitable for Flow Cyt,ICC or IHC-P.
  • 靶标

    • 功能This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
    • 序列相似性Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
    • 翻译后修饰Phosphorylation on Tyr-10 modulates pumping activity.
    • 细胞定位Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A1A1 antibody
      • AT1A1 antibody
      • AT1A1_HUMAN antibody
      • ATP1A1 antibody
      • Atpa-1 antibody
      • ATPase Na+/K+ transporting alpha 1 polypeptide antibody
      • ATPase Na+/K+ transporting subunit alpha 1 antibody
      • BC010319 antibody
      • EC antibody
      • MGC3285 antibody
      • MGC38419 antibody
      • MGC51750 antibody
      • Na K ATPase alpha A catalytic polypeptide antibody
      • Na K ATPase catalytic subunit alpha A protein antibody
      • Na(+)/K(+) ATPase 1 antibody
      • Na(+)/K(+) ATPase alpha-1 subunit antibody
      • Na+, K+ ATPase alpha subunit antibody
      • Na+/K+ ATPase alpha 1 subunit antibody
      • Na+/K+ ATPase 1 antibody
      • Na,K ATPase alpha 1 subunit antibody
      • Nkaa1b antibody
      • Sodium potassium ATPase alpha 1 polypeptide antibody
      • Sodium pump 1 antibody
      • Sodium pump subunit alpha-1 antibody
      • sodium-potassium ATPase catalytic subunit alpha-1 antibody
      • Sodium/potassium-transporting ATPase subunit alpha-1 antibody
      see all

    Anti-alpha 1 Sodium Potassium ATPase (phospho Y10) antibody [EPR2375(2)] 图像

    • All lanes : Anti-alpha 1 Sodium Potassium ATPase (phospho Y10) antibody [EPR2375(2)] (ab124677) at 1/10000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HeLa cell lysate, treated with Pervanadate

      Lysates/proteins at 10 µg per lane.

      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 113 kDa
      Observed band size : 100 kDa (why is the actual band size different from the predicted?)

    Anti-alpha 1 Sodium Potassium ATPase (phospho Y10) antibody [EPR2375(2)] (ab124677)参考文献

    ab124677 has not yet been referenced specifically in any publications.

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