Anti-alpha 1 Sodium Potassium ATPase抗体(ab33133)

概述

  • 产品名称
    Anti-alpha 1 Sodium Potassium ATPase抗体
    参阅全部 alpha 1 Sodium Potassium ATPase 一抗
  • 描述
    兔多克隆抗体to alpha 1 Sodium Potassium ATPase
  • 特异性
    Ab33133 recognises alpha 1 subunit of Sodium Potassium ATPase.
  • 经测试应用
    适用于: IP, IHC-Frmore details
  • 种属反应性
    与反应: Rat, Cow
    不与反应: Rabbit
  • 免疫原

    Fusion protein, corresponding to amino acids 338-518 of Rat alpha 1 Sodium Potassium ATPase.

  • 阳性对照
    • WB: Rat kidney microsomes. IP: Rat kidney and brai microsomes. ICC/IHC-Fr: Rat kidney and brain.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 0.05% Sodium Azide
    Constituents: 40% Glycerol, 150mM Sodium chloride, 100mM Tris glycine. pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab33133 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use a concentration of 4 µg/ml. Use 4 µg to immunoprecipate the a 1 subunit from 500 µg rat kidney microsomes.
IHC-Fr 1/5. Use at a concentration of 5 µg/ml to detect the a 1 subunit in frozen sections of rat kidney and brain, which were fixed in 4% paraformaldehyde.

靶标

  • 功能
    This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
  • 序列相似性
    Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
  • 翻译后修饰
    Phosphorylation on Tyr-10 modulates pumping activity.
  • 细胞定位
    Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A1A1 antibody
    • AT1A1 antibody
    • AT1A1_HUMAN antibody
    • ATP1A1 antibody
    • Atpa-1 antibody
    • ATPase Na+/K+ transporting alpha 1 polypeptide antibody
    • ATPase Na+/K+ transporting subunit alpha 1 antibody
    • BC010319 antibody
    • EC 3.6.3.9 antibody
    • MGC3285 antibody
    • MGC38419 antibody
    • MGC51750 antibody
    • Na K ATPase alpha A catalytic polypeptide antibody
    • Na K ATPase catalytic subunit alpha A protein antibody
    • Na(+)/K(+) ATPase 1 antibody
    • Na(+)/K(+) ATPase alpha-1 subunit antibody
    • Na+, K+ ATPase alpha subunit antibody
    • Na+/K+ ATPase alpha 1 subunit antibody
    • Na+/K+ ATPase 1 antibody
    • Na,K ATPase alpha 1 subunit antibody
    • Nkaa1b antibody
    • Sodium potassium ATPase alpha 1 polypeptide antibody
    • Sodium pump 1 antibody
    • Sodium pump subunit alpha-1 antibody
    • sodium-potassium ATPase catalytic subunit alpha-1 antibody
    • Sodium/potassium-transporting ATPase subunit alpha-1 antibody
    see all

文献

This product has been referenced in:
  • Mahendrasingam S  et al. Subcellular distribution and relative expression of fibrocyte markers in the CD/1 mouse cochlea assessed by semiquantitative immunogold electron microscopy. J Histochem Cytochem 59:984-1000 (2011). Read more (PubMed: 22043022) »

See 1 Publication for this product

客户评价及客户问答

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There are several antibodies in our catalogue targeting either the alpha or beta subunit of Sodium Potassium ATPase.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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