Anti-alpha 1 Glycine Receptor抗体(ab55057)

概述

  • 产品名称Anti-alpha 1 Glycine Receptor抗体
    参阅全部 alpha 1 Glycine Receptor 一抗
  • 描述
    小鼠单克隆抗体to alpha 1 Glycine Receptor
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: IWKPDLFFAN EKGAHFHEIT TDNKLLRISR NGNVLYSIRI TLTLACPMDL KNFPMDVQTC IMQLESFGYT MNDLIFEWQE QGAVQVADGL TLPQFILKEE , corresponding to amino acids 121-221 of Human alpha 1 Glycine Receptor

性能

应用

Our Abpromise guarantee covers the use of ab55057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
    • 疾病相关Defects in GLRA1 are a cause of startle disease (STHE) [MIM:149400]; also known as hereditary hyperekplexia or congenital stiff-person syndrome. STHE is a genetically heterogeneous neurologic disorder characterized by muscular rigidity of central nervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpected acoustic or tactile stimuli. Inheritance can be autosomal dominant or recessive.
    • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
    • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • GLRA1 antibody
      • GLRA1_HUMAN antibody
      • Glycine receptor 48 kDa subunit antibody
      • Glycine receptor alpha 1 antibody
      • Glycine receptor strychnine-binding subunit antibody
      • Glycine receptor subunit alpha-1 antibody
      • Glycine receptor, alpha 1 subunit antibody
      • HKPX1 antibody
      • STHE antibody
      see all

    Anti-alpha 1 Glycine Receptor antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab55057 alpha 1 Glycine Receptor antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-alpha 1 Glycine Receptor antibody (ab55057)参考文献

    ab55057 has not yet been referenced specifically in any publications.

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