Anti-alpha 1 Fetoprotein抗体[EP1017Y] (ab45147)


  • 产品名称Anti-alpha 1 Fetoprotein抗体[EP1017Y]
    参阅全部 alpha 1 Fetoprotein 一抗
  • 描述
    兔单克隆抗体[EP1017Y] to alpha 1 Fetoprotein
  • 经测试应用适用于: WB, IHC-P, IPmore details
    不适用于: Flow Cyt or ICC/IF
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human alpha 1 Fetoprotein (C terminal).

  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.


    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab45147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/2000. Predicted molecular weight: 69 kDa.
IHC-P Use at an assay dependent concentration.
IP 1/50.
  • 应用说明Is unsuitable for Flow Cyt or ICC/IF.
  • 靶标

    • 功能Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
    • 组织特异性Plasma. Synthesized by the fetal liver and yolk sac.
    • 序列相似性Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • 发展阶段Occurs in the plasma of fetuses more than 4 weeks old, reaches the highest levels during the 12th-16th week of gestation, and drops to trace amounts after birth. The serum level in adults is usually less than 40 ng/ml. AFP occurs also at high levels in the plasma and ascitic fluid of adults with hepatoma.
    • 翻译后修饰Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Afp antibody
      • Alpha fetoglobulin antibody
      • Alpha fetoprotein antibody
      • Alpha fetoprotein precursor antibody
      • Alpha-1-fetoprotein antibody
      • Alpha-fetoglobulin antibody
      • Alpha-fetoprotein antibody
      • alpha-fetoprotein, Hereditary persistence of, included antibody
      • FETA antibody
      • FETA_HUMAN antibody
      • Hereditary persistence of alpha fetoprotein antibody
      • HPAFP antibody
      see all

    Anti-alpha 1 Fetoprotein antibody [EP1017Y] 图像

    • Anti-alpha 1 Fetoprotein antibody [EP1017Y] (ab45147) at 1/50000 dilution + HepG2 membrane

      Predicted band size : 69 kDa
      Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    • Ab45147 staining human alpha 1 Fetoprotein in human fetal liver by immunohistochemistry using paraffin embedded tissue.

    Anti-alpha 1 Fetoprotein antibody [EP1017Y] (ab45147)参考文献

    This product has been referenced in:
    • Joshi M  et al. Chemokine-mediated robust augmentation of liver engraftment: a novel approach. Stem Cells Transl Med 4:21-30 (2015). Read more (PubMed: 25473087) »

    See 1 Publication for this product

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