Anti-alpha 1 Fetoprotein抗体(ab8202)

概述

  • 产品名称Anti-alpha 1 Fetoprotein抗体
    参阅全部 alpha 1 Fetoprotein 一抗
  • 描述
    山羊多克隆抗体to alpha 1 Fetoprotein
  • 特异性Specificity of the antisera is confirmed by ELISA (OPD) on human alpha-Fetoprotein versus albumin, IgG, IgM. Tests with immunoblotting of fetal and adult sera. Ouchterlony double diffusion, immunoelectrophoresis. No crossreactivity with human plasma proteins.
  • 经测试应用适用于: WB, ELISA, Agglutinationmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein (Human).

性能

应用

Our Abpromise guarantee covers the use of ab8202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
AP
Agglutination
  • 应用说明Recommended for immunoblotting. Sandwich-ELISA with monoclonal antibody to AFP (ab8198 and ab8199 sensitivity 0.5 ng/ml). Affinity chromatography with antibody-sorbent for isolation of 85% pure AFP. Latex coating for APF agglutination assay.
  • 靶标

    • 功能Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
    • 组织特异性Plasma. Synthesized by the fetal liver and yolk sac.
    • 序列相似性Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • 发展阶段Occurs in the plasma of fetuses more than 4 weeks old, reaches the highest levels during the 12th-16th week of gestation, and drops to trace amounts after birth. The serum level in adults is usually less than 40 ng/ml. AFP occurs also at high levels in the plasma and ascitic fluid of adults with hepatoma.
    • 翻译后修饰Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence.
      Sulfated.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Afp antibody
      • Alpha fetoglobulin antibody
      • Alpha fetoprotein antibody
      • Alpha fetoprotein precursor antibody
      • Alpha-1-fetoprotein antibody
      • Alpha-fetoglobulin antibody
      • Alpha-fetoprotein antibody
      • alpha-fetoprotein, Hereditary persistence of, included antibody
      • FETA antibody
      • FETA_HUMAN antibody
      • Hereditary persistence of alpha fetoprotein antibody
      • HPAFP antibody
      see all

    Anti-alpha 1 Fetoprotein antibody (ab8202)参考文献

    ab8202 has not yet been referenced specifically in any publications.

    Product Wall

    I am sorry for the inconvenience caused by this import restriction. While ab3980 is our only Anti-alpha 1 Fetoprotein raised in goat, we do offer a number of other Anti-alpha 1 Fetoprotein. We would recommend use of ab3980, Mouse monoclonal [AFP-01] to...

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    Thank you for your request. This product (Alpha Fetoprotein antibody Ref:ab8202) has not yet been tested for cross-reactivity with mouse AFP, therefore we cannot guarantee results.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"