Anti-alpha 1 Catenin抗体(ab110044)


  • 产品名称Anti-alpha 1 Catenin抗体
    参阅全部 alpha 1 Catenin 一抗
  • 描述
    山羊多克隆抗体to alpha 1 Catenin
  • 经测试应用适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Chicken, Cow, Dog, Xenopus laevis, Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide:


    , corresponding to internal sequence amino acids 871-883 of Human alpha 1 Catenin

  • 阳性对照
    • Human Prostate and Uterus tissue. Human colon lysate.



Our Abpromise guarantee covers the use of ab110044 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/32000.
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 100 kDa.
IHC-P Use a concentration of 3.75 µg/ml.


  • 功能Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
  • 组织特异性Expressed ubiquitously in normal tissues.
  • 序列相似性Belongs to the vinculin/alpha-catenin family.
  • 翻译后修饰Sumoylated.
  • 细胞定位Cell membrane and Cytoplasm > cytoskeleton. Cell junction > adherens junction. Cell membrane. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha E-catenin antibody
    • Cadherin associated protein 102kDa antibody
    • Cadherin associated protein antibody
    • Cadherin-associated protein antibody
    • CAP 102 antibody
    • CAP102 antibody
    • Catenin (cadherin associated protein) alpha 1 102kDa antibody
    • Catenin (cadherin associated protein), alpha 1, 102kDa antibody
    • Catenin alpha 1 antibody
    • Catenin alpha-1 antibody
    • CTNA1_HUMAN antibody
    • CTNNA 1 antibody
    • Ctnna1 antibody
    • FLJ36832 antibody
    • FLJ52416 antibody
    • NY REN 13 antigen antibody
    • OTTHUMP00000224141 antibody
    • OTTHUMP00000224147 antibody
    • Renal carcinoma antigen NY REN 13 antibody
    • Renal carcinoma antigen NY-REN-13 antibody
    see all

Anti-alpha 1 Catenin antibody 图像

  • Anti-alpha 1 Catenin antibody (ab110044) at 1 µg/ml (incubated for 1 hour) + Human colon lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 100 kDa
  • ab110044 at 3.75 µg/ml staining alpha 1 Catenin in Formalin-Fixed, Paraffin-Embedded Human Prostate by Immunohistochemistry.
  • ab110044 at 3.75 µg/ml staining alpha 1 Catenin in Formalin-Fixed, Paraffin-Embedded Human Uterus by Immunohistochemistry.

Anti-alpha 1 Catenin antibody (ab110044)参考文献

ab110044 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110044.
Please use the links above to contact us or submit feedback about this product.