概述

  • 产品名称Anti-ALG9抗体
    参阅全部 ALG9 一抗
  • 描述
    兔多克隆抗体to ALG9
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide between amino acids 532-559 from the C terminal region of Human ALG9 (NP_001071159.1, NP_001071160.1, NP_001071158.1, NP_079016.2).

  • 阳性对照
    • Ramos cell line lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab107072 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 70 kDa.

靶标

  • 功能Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides.
  • 组织特异性Ubiquitously expressed; with highest levels in heart, liver and pancreas.
  • 通路Protein modification; protein glycosylation.
  • 疾病相关Note=A chromosomal aberration involving ALG9 is found in a family with bipolar affective disorder. Translocation t(9;11)(p24;q23). However, common variations in ALG9 do not play a major role in predisposition to bipolar affective disorder.
    Defects in ALG9 are the cause of congenital disorder of glycosylation type 1L (CDG1L) [MIM:608776]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 序列相似性Belongs to the glycosyltransferase 22 family.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ALG9 antibody
    • ALG9_HUMAN antibody
    • Alpha-1,2-mannosyltransferase ALG9 antibody
    • Asparagine-linked glycosylation protein 9 homolog antibody
    • Disrupted in bipolar disorder protein 1 antibody
    see all

Anti-ALG9 antibody 图像

  • Anti-ALG9 antibody (ab107072) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 70 kDa

Anti-ALG9 antibody (ab107072)参考文献

ab107072 has not yet been referenced specifically in any publications.

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