概述

  • 产品名称Anti-ALG11抗体
    参阅全部 ALG11 一抗
  • 描述
    兔多克隆抗体to ALG11
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C-terminal amino acids 343-373 of Human ALG11 (NP_001004127.2, Q2TAA5).

  • 阳性对照
    • HepG2 cell line lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified through a Protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.

靶标

  • 功能Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain.
  • 疾病相关Defects in ALG11 are the cause of congenital disorder of glycosylation type 1P (CDG1P) [MIM:613661]. A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 序列相似性Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  • 细胞定位Endoplasmic reticulum. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI849156 antibody
    • alg11 antibody
    • ALG11_HUMAN antibody
    • Asparagine-linked glycosylation 11 antibody
    • Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) antibody
    • Asparagine-linked glycosylation protein 11 homolog antibody
    • AW492253 antibody
    • B230397C21 antibody
    • GT8 antibody
    • KIAA0266 antibody
    • OTTMUSP00000022781 antibody
    • RGD1564725 antibody
    see all

Anti-ALG11 antibody 图像

  • Anti-ALG11 antibody (ab123723) at 1/100 dilution + HepG2 cell line lysate at 35 µg

    Predicted band size : 56 kDa

Anti-ALG11 antibody (ab123723)参考文献

ab123723 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123723.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"