概述

  • 产品名称Anti-ALDOB抗体[EPR3138Y]
    参阅全部 ALDOB 一抗
  • 描述
    兔单克隆抗体[EPR3138Y] to ALDOB
  • 经测试应用适用于: WB, IHC-P, Flow Cytmore details
    不适用于: ICC or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in human ALDOB.

  • 阳性对照
    • Fetal kidney lysate. Human liver tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

     

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab75751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 39 kDa.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/20.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • 应用说明Is unsuitable for ICC or IP.
  • 靶标

    • 通路Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.
    • 疾病相关Defects in ALDOB are the cause of hereditary fructose intolerance (HFI) [MIM:229600]. HFI is an autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.
    • 序列相似性Belongs to the class I fructose-bisphosphate aldolase family.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ALDB antibody
      • ALDO B antibody
      • ALDO2 antibody
      • ALDOB antibody
      • ALDOB_HUMAN antibody
      • Aldolase 2 antibody
      • Aldolase B antibody
      • Aldolase B fructose bisphosphate antibody
      • Aldolase2 antibody
      • AldolaseB antibody
      • EC 4.1.2.13 antibody
      • Fructose bisphosphate aldolase B antibody
      • Fructose-bisphosphate aldolase B antibody
      • Liver type aldolase antibody
      • Liver-type aldolase antibody
      • MS1077 antibody
      see all

    Anti-ALDOB antibody [EPR3138Y] 图像

    • Anti-ALDOB antibody [EPR3138Y] (ab75751) at 1/1000 dilution + fetal kidney lysate at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 39 kDa
      Observed band size : 39 kDa
    • ab75751, at 1/100 dilution, staining ALDOB in paraffin-embedded human liver tissue.
    • ab75751 showing positive staining in Normal kidney tissue.

    • ab75751 showing negative staining in Normal colon tissue.

    • ab75751 showing negative staining in Normal lung tissue.

    • ab75751 showing negative staining in Normal tonsil tissue.

    Anti-ALDOB antibody [EPR3138Y] (ab75751)参考文献

    This product has been referenced in:
    • Wang C  et al. Long-term supranutritional supplementation with selenate decreases hyperglycemia and promotes fatty liver degeneration by inducing hyperinsulinemia in diabetic db/db mice. PLoS One 9:e101315 (2014). WB . Read more (PubMed: 24983750) »
    • Tun HW  et al. Pathway signature and cellular differentiation in clear cell renal cell carcinoma. PLoS One 5:e10696 (2010). IHC-P ; Human . Read more (PubMed: 20502531) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab75751.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"