The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Predicted molecular weight: 54 kDa.
Use at an assay dependent concentration.
功能Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction.
组织特异性High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole.
通路Amine and polyamine biosynthesis; carnitine biosynthesis.
序列相似性Belongs to the aldehyde dehydrogenase family.
发展阶段Strongly expressed in human embryonic brain (gestational age 12 weeks).