概述

  • 产品名称Anti-ALDH6A1抗体
    参阅全部 ALDH6A1 一抗
  • 描述
    兔多克隆抗体to ALDH6A1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide within residues: VLVGEAKKWL PELVEHAKNL RVNAGDQPGA DLGPLITPQA KERVCNLIDS , corresponding to internal sequence amino acids 324-373 of Human ALDH6A1 (NP_005580)

  • 阳性对照
    • Human fetal kidney lysate.

性能

应用

Our Abpromise guarantee covers the use of ab89705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
  • 疾病相关Defects in ALDH6A1 are the cause of methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency) [MIM:603178]. This is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
  • 序列相似性Belongs to the aldehyde dehydrogenase family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1110038I05Rik antibody
    • AI314632 antibody
    • Aldehyde dehydrogenase 6 family member A1 antibody
    • Aldehyde dehydrogenase family 6 member A1 antibody
    • Aldehyde dehydrogenase family 6, subfamily A1 antibody
    • ALDH6A1 antibody
    • Malonate semialdehyde dehydrogenase antibody
    • Malonate-semialdehyde dehydrogenase [acylating] antibody
    • Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody
    • Methylmalonate-semialdehyde dehydrogenase [acylating] antibody
    • MGC37325 antibody
    • MGC40271 antibody
    • Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody
    • mitochondrial antibody
    • MMSA_HUMAN antibody
    • MMSADHA antibody
    • MMSDH antibody
    see all

Anti-ALDH6A1 antibody 图像

  • Anti-ALDH6A1 antibody (ab89705) at 1 µg/ml + human fetal kidney lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 54 kDa
    Observed band size : 54 kDa

Anti-ALDH6A1 antibody (ab89705)参考文献

ab89705 has not yet been referenced specifically in any publications.

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