产品名称 Anti-ALDH5A1抗体 参阅全部 ALDH5A1 一抗
特异性 ab106819 is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1).
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Mouse, Rat, Human
Cow, Dog, Orangutan
C-TGKILLHHAANS , corresponding to internal sequence amino acids 288-299 of Human ALDH5A1 (NP_733936.1; NP_001071.1).
Human, Mouse and Rat Liver lysates.
存放说明 Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
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纯度 Immunogen affinity purified
纯化说明 ab106819 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 57 kDa.
功能 Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
组织特异性 Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
通路 Amino-acid degradation; 4-aminobutanoate degradation.
疾病相关 Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development.
序列相似性 Belongs to the aldehyde dehydrogenase family.
Information by UniProt
Aldedehyde dehydrogenase 5 family antibody
Aldehyde dehydrogenase 5 family member A1 antibody
Aldehyde dehydrogenase 5A1 antibody
Anti-ALDH5A1 antibody (ab106819)参考文献
has not yet been referenced specifically in any publications.
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