概述

  • 产品名称Anti-Albumin抗体
    参阅全部 Albumin 一抗
  • 描述
    鸡多克隆抗体to Albumin
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human Albumin (internal sequence).
    Database link: P02768

  • 阳性对照
    • Mouse liver lysate; Human liver tissue
  • 常规说明

    Antibodies should not be exposed to prolonged high temperatures.

性能

应用

Our Abpromise guarantee covers the use of ab106582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa.
IHC-P Use a concentration of 2.5 - 20 µg/ml.
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
  • 组织特异性Plasma.
  • 疾病相关Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
  • 序列相似性Belongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • 翻译后修饰Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
    Glycated in diabetic patients.
    Phosphorylation sites are present in the extracelllular medium.
    Acetylated on Lys-223 by acetylsalicylic acid.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 形式There are 2 isoforms produced by alternative splicing.
  • 别名
    • alb antibody
    • ALBU_HUMAN antibody
    • Albumin (32 AA) antibody
    • Albumin (AA 34) antibody
    • cell growth inhibiting protein 42 antibody
    • DKFZp779N1935 antibody
    • GIG20 antibody
    • GIG42 antibody
    • growth-inhibiting protein 20 antibody
    • OTTHUMP00000220436 antibody
    • OTTHUMP00000220438 antibody
    • OTTHUMP00000220439 antibody
    • PRO0883 antibody
    • PRO0903 antibody
    • PRO1341 antibody
    • PRO1708 antibody
    • PRO2044 antibody
    • PRO2619 antibody
    • PRO2675 antibody
    • Serum albumin antibody
    • UNQ696/PRO1341 antibody
    see all

Anti-Albumin antibody 图像

  • Lane 1 : Anti-Albumin antibody (ab106582) at 1 µg/ml
    Lane 2 : Anti-Albumin antibody (ab106582) at 2 µg/ml

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : Mouse liver tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 69 kDa
  • Immunohistochemical analysis of paraffin embedded Human liver tissue section labelling Albumin with ab106582 at 2.5 µg/ml. 

  • Immunohistochemical analysis of paraffin embedded Human liver tissue section labelling Albumin with ab106582 at 20 µg/mL. 

  • Immunohistochemical analysis of paraffin embedded Mouse liver tissue section labelling Albumin with ab106582 at 5 µg/ml. 

Anti-Albumin antibody (ab106582)参考文献

This product has been referenced in:
  • Zhai W  et al. A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway. Mol Brain 9:66 (2016). Rat . Read more (PubMed: 27301321) »
  • Ma J  et al. Pramipexole-Induced Hypothermia Reduces Early Brain Injury via PI3K/AKT/GSK3ß pathway in Subarachnoid Hemorrhage rats. Sci Rep 6:23817 (2016). WB ; Rat . Read more (PubMed: 27026509) »

See all 4 Publications for this product

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Blocking step BSA as blocking agent for 20 minute(s) · Concentration: 5% · Temperature: RT°C
Sample Human Cell (T98G Human brain glioblastoma)
Specification T98G Human brain glioblastoma
Permeabilization Yes - 0.1% v/v Triton X-100 pH 7.4 for 5 min at RT
Fixative Paraformaldehyde
Username

Dr. Dimitra Kalamida

Verified customer

提交于 Feb 03 2014

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I am very pleased to hear you would like to accept our offer and test ab106582/ab131176 in Flow Cytometry. This code will give you: 1 free PRIMARY ANTIBODY per discount codebefore the expi...

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Thank you for contacting us.

Indeed, I am happy to let you know that we have anti-rat albumin antibodies (unconjugated and conjugated) available:
ab106582:Click here (or use the following: http://www.abcam.com/index.html?datasheet=10658...

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Thanks for your reply. Either one of these 2 anti-albumin antibodies may work in flow although neither has yet been tested in that application. However we can't guarantee that they will work in flow. As we can't offer our Abpromise guarantee for flow w...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"