概述

  • 产品名称Anti-AKR7A2抗体
    参阅全部 AKR7A2 一抗
  • 描述
    兔多克隆抗体to AKR7A2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the N-terminal region of human AKR7A2.

  • 阳性对照
    • Mouse liver golgi apparatus lysate

性能

应用

Our Abpromise guarantee covers the use of ab82397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
ELISA 1/1000.

靶标

  • 功能Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
  • 组织特异性Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed.
  • 序列相似性Belongs to the aldo/keto reductase 2 family.
  • 细胞定位Golgi apparatus. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AFAR antibody
    • AFAR1 antibody
    • AFB1 aldehyde reductase 1 antibody
    • AFB1 AR1 antibody
    • AFB1-AR 1 antibody
    • AFB1AR1 antibody
    • Aflatoxin aldehyde reductase antibody
    • Aflatoxin B1 aldehyde reductase member 2 antibody
    • Aflatoxin beta1 aldehyde reductase antibody
    • Aiar antibody
    • AKR7 antibody
    • Akr7a2 antibody
    • Aldo keto reductase family 7 antibody
    • Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody
    • Aldo keto reductase family 7 member A2 antibody
    • Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase) antibody
    • Aldoketoreductase 7 antibody
    • ARK72_HUMAN antibody
    • SSA reductase antibody
    • Succinic semialdehyde reductase antibody
    see all

Anti-AKR7A2 antibody 图像

  • Anti-AKR7A2 antibody (ab82397) at 1/50 dilution + Mouse liver tissue lysates at 12.5 µg

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.

Anti-AKR7A2 antibody (ab82397)参考文献

ab82397 has not yet been referenced specifically in any publications.

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