概述

  • 产品名称Anti-AKR1D1抗体
    参阅全部 AKR1D1 一抗
  • 描述
    小鼠单克隆抗体to AKR1D1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: NPIWVNVSSP PLLKDALLNS LGKRYNKTAA QIVLRFNIQR GVVVIPKSFN LERIKENFQI FDFSLTEEEM KDIEALNKNV RFVELLMWRD HPEYPFHDEY , corresponding to amino acids 227-327 of Human AKR1D1

性能

应用

Our Abpromise guarantee covers the use of ab57993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
    • 组织特异性Highly expressed in liver. Expressed in testis and weakly in colon.
    • 疾病相关Congenital bile acid synthesis defect 2
    • 序列相似性Belongs to the aldo/keto reductase family.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 3-oxo-5-beta-steroid 4-dehydrogenase antibody
      • 3o5bred antibody
      • AK1D1_HUMAN antibody
      • AKR1D1 antibody
      • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody
      • Aldo keto reductase family 1 member D1 antibody
      • Aldo-keto reductase family 1 member D1 antibody
      • CBAS2 antibody
      • Delta(4) 3 ketosteroid 5 beta reductase antibody
      • Delta(4) 3 oxosteroid 5 beta reductase antibody
      • Delta(4)-3-ketosteroid 5-beta-reductase antibody
      • Delta(4)-3-oxosteroid 5-beta-reductase antibody
      • SRD5B1 antibody
      • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody
      • steroid 5 beta reductase antibody
      see all

    Anti-AKR1D1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57993 AKR1D1 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    Anti-AKR1D1 antibody (ab57993)参考文献

    ab57993 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"