Recombinant protein fragment containing a sequence corresponding to a region within amino acids 184 and 322 of AKR1D1 (AAI30626).
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 37 kDa.
Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
Highly expressed in liver. Expressed in testis and weakly in colon.
Congenital bile acid synthesis defect 2
Belongs to the aldo/keto reductase family.
Information by UniProt
3-oxo-5-beta-steroid 4-dehydrogenase antibody
has not yet been referenced specifically in any publications.
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