概述

  • 产品名称
    Anti-AKR1D1抗体
  • 描述
    兔多克隆抗体to AKR1D1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 184 and 322 of AKR1D1 (AAI30626).

  • 阳性对照
    • A549 whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab101393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.

靶标

  • 功能
    Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4-cholesten-3-one can also act as substrates.
  • 组织特异性
    Highly expressed in liver. Expressed in testis and weakly in colon.
  • 疾病相关
    Congenital bile acid synthesis defect 2
  • 序列相似性
    Belongs to the aldo/keto reductase family.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3-oxo-5-beta-steroid 4-dehydrogenase antibody
    • 3o5bred antibody
    • AK1D1_HUMAN antibody
    • AKR1D1 antibody
    • aldo keto reductase family 1 member D1 (delta 4 3 ketosteroid 5 beta reductase) antibody
    • Aldo keto reductase family 1 member D1 antibody
    • Aldo-keto reductase family 1 member D1 antibody
    • CBAS2 antibody
    • Delta(4) 3 ketosteroid 5 beta reductase antibody
    • Delta(4) 3 oxosteroid 5 beta reductase antibody
    • Delta(4)-3-ketosteroid 5-beta-reductase antibody
    • Delta(4)-3-oxosteroid 5-beta-reductase antibody
    • SRD5B1 antibody
    • steroid 5 beta reductase beta polypeptide 1 (3 oxo 5 beta steroid delta 4 dehydrogenase beta 1) antibody
    • steroid 5 beta reductase antibody
    see all

图片

  • Anti-AKR1D1 antibody (ab101393) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 37 kDa

实验方案

文献

ab101393 has not yet been referenced specifically in any publications.

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