概述

  • 产品名称Anti-AKR1B10抗体
    参阅全部 AKR1B10 一抗
  • 描述
    小鼠单克隆抗体to AKR1B10
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: VSKLWPTFFE RPLVRKAFEK TLKDLKLSYL DVYLIHWPQG FKSGDDLFPK DDKGNAIGGK ATFLDAWE, corresponding to amino acids 76-144 of Human AKR1B10

性能

应用

Our Abpromise guarantee covers the use of ab57547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 36 kDa.
IHC-P Use a concentration of 3 µg/ml.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
  • 组织特异性Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
  • 序列相似性Belongs to the aldo/keto reductase family.
  • 细胞定位Lysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AK1BA_HUMAN antibody
    • AKR1B10 antibody
    • AKR1B11 antibody
    • AKR1B12 antibody
    • Aldo keto reductase family 1 member B10 antibody
    • aldo keto reductase family 1 member B11 antibody
    • Aldo-keto reductase family 1 member B10 (aldose reductase) antibody
    • Aldo-keto reductase family 1 member B10 antibody
    • Aldo-keto reductase family 1 member B11 (aldose reductase-like) antibody
    • aldose reductase like 1 antibody
    • Aldose reductase like antibody
    • aldose reductase like peptide antibody
    • Aldose reductase related protein antibody
    • Aldose reductase-like antibody
    • Aldose reductase-related protein antibody
    • ALDRLn antibody
    • ARL 1 antibody
    • ARL-1 antibody
    • ARL1 antibody
    • ARL1 Human small intestine reductase antibody
    • ARP antibody
    • hARP antibody
    • HIS antibody
    • HSI antibody
    • SI reductase antibody
    • Small intestine reductase antibody
    see all

Anti-AKR1B10 antibody 图像

  • AKR1B10 antibody (ab57547) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon.


  • Predicted band size : 36 kDa
    AKR1B10 antibody (ab57547) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
  • Immunocytochemistry/Immunofluorescence analysis of HeLa cells labeling AKR1B10 with ab57547 at 10µg/ml.

Anti-AKR1B10 antibody (ab57547)参考文献

This product has been referenced in:
  • Tsuzura H  et al. Expression of aldo-keto reductase family 1 member b10 in the early stages of human hepatocarcinogenesis. Int J Mol Sci 15:6556-68 (2014). IHC-P ; Human . Read more (PubMed: 24747592) »
  • Kikuchi T  et al. In-depth proteomic analysis of nonsmall cell lung cancer to discover molecular targets and candidate biomarkers. Mol Cell Proteomics 11:916-32 (2012). WB ; Human . Read more (PubMed: 22761400) »

See all 2 Publications for this product

Product Wall

Thank you very much for your interest in ab57547.

I have confirmed with the laboratory that unfortunately we have not measured the Kd value for this antibody, nor has it been tested in ELISA.

To our knowledge, ab57547 has not been...

Read More
Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Tonsillar mucosal epithelium)
Specification Tonsillar mucosal epithelium
Fixative Formaldehyde
Antigen retrieval step Heat mediated
Permeabilization No
Blocking step BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 22°C
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提交于 Nov 13 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"