概述

  • 产品名称Anti-AKR1B10抗体[1A6]
    参阅全部 AKR1B10 一抗
  • 描述
    小鼠单克隆抗体[1A6] to AKR1B10
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to internal sequence amino acids 76-144 of Human AKR1B10, with a proprietary tag (NP_064695).

  • 阳性对照
    • Human small intestine tissue, Human kidney tissue, Human liver tissue, HeLa cells, HepG2 cell lysate, recombinant GST tagged AKR1B10.

性能

应用

Our Abpromise guarantee covers the use of ab109998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 36 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
  • 组织特异性Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
  • 序列相似性Belongs to the aldo/keto reductase family.
  • 细胞定位Lysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AK1BA_HUMAN antibody
    • AKR1B10 antibody
    • AKR1B11 antibody
    • AKR1B12 antibody
    • Aldo keto reductase family 1 member B10 antibody
    • aldo keto reductase family 1 member B11 antibody
    • Aldo-keto reductase family 1 member B10 (aldose reductase) antibody
    • Aldo-keto reductase family 1 member B10 antibody
    • Aldo-keto reductase family 1 member B11 (aldose reductase-like) antibody
    • aldose reductase like 1 antibody
    • Aldose reductase like antibody
    • aldose reductase like peptide antibody
    • Aldose reductase related protein antibody
    • Aldose reductase-like antibody
    • Aldose reductase-related protein antibody
    • ALDRLn antibody
    • ARL 1 antibody
    • ARL-1 antibody
    • ARL1 antibody
    • ARL1 Human small intestine reductase antibody
    • ARP antibody
    • hARP antibody
    • HIS antibody
    • HSI antibody
    • SI reductase antibody
    • Small intestine reductase antibody
    see all

Anti-AKR1B10 antibody [1A6] 图像

  • ab109998, at 5 µg/ml, staining AKR1B10 in Human small intenstine tissue by immunohistochemistry.
  • ab109998, at 5 µg/ml, staining AKR1B10 in Human kidney tissue by immunohistochemistry.
  • ab109998, at 5 µg/ml, staining AKR1B10 in Human liver tissue by immunohistochemistry.
  • Anti-AKR1B10 antibody [1A6] (ab109998) + HepG2 cell lysate

    Predicted band size : 36 kDa
  • ab109998, at 10 µg/ml, staining AKR1B10 in HeLa cells by immunoflourescence.

Anti-AKR1B10 antibody [1A6] (ab109998)参考文献

This product has been referenced in:
  • Agyeman AS  et al. Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles. Breast Cancer Res Treat 132:175-87 (2012). WB ; Rat . Read more (PubMed: 21597922) »

See 1 Publication for this product

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