Anti-AKR1A1抗体- C-terminal (ab71228)

概述

  • 产品名称Anti-AKR1A1抗体- C-terminal
    参阅全部 AKR1A1 一抗
  • 描述
    兔多克隆抗体to AKR1A1 - C-terminal
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 阳性对照
    • Y79 cell line lysates.

性能

应用

Our Abpromise guarantee covers the use of ab71228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/10 - 1/50.
ELISA 1/1000.
WB 1/50 - 1/100. Predicted molecular weight: 37 kDa.

靶标

  • 功能Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
  • 组织特异性Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
  • 序列相似性Belongs to the aldo/keto reductase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AK1A1_HUMAN antibody
    • Akr1a1 antibody
    • Alcohol dehydrogenase [NADP+] antibody
    • Alcohol dehydrogenase antibody
    • Aldehyde reductase antibody
    • Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody
    • Aldo-keto reductase family 1 member A1 antibody
    • ALDR1 antibody
    • ALR antibody
    • ARM antibody
    • DD3 antibody
    • MGC12529 antibody
    • MGC1380 antibody
    see all

Anti-AKR1A1 antibody - C-terminal 图像

  • Anti-AKR1A1 antibody - C-terminal (ab71228) at 1/60 dilution + Y79 cell line lysates at 35 µg

    Predicted band size : 37 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
  • ab71228 at 1/50 dilution staining AKR1A1 - C-terminal in human Hepatocarcinoma tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A peroxidase conjugated secondary antibody was used followed by DAB staining.

Anti-AKR1A1 antibody - C-terminal (ab71228)参考文献

ab71228 has not yet been referenced specifically in any publications.

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