概述

  • 产品名称Anti-AKR1A1抗体
    参阅全部 AKR1A1 一抗
  • 描述
    兔多克隆抗体to AKR1A1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Cow, Pig
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1 - 131 of Human AKR1A1 (P14550).

  • 阳性对照
    • A549 whole cell lysate HepG2 whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab125878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.

靶标

  • 功能Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
  • 组织特异性Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
  • 序列相似性Belongs to the aldo/keto reductase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AK1A1_HUMAN antibody
    • Akr1a1 antibody
    • Alcohol dehydrogenase [NADP+] antibody
    • Alcohol dehydrogenase antibody
    • Aldehyde reductase antibody
    • Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody
    • Aldo-keto reductase family 1 member A1 antibody
    • ALDR1 antibody
    • ALR antibody
    • ARM antibody
    • DD3 antibody
    • MGC12529 antibody
    • MGC1380 antibody
    see all

Anti-AKR1A1 antibody 图像

  • All lanes : Anti-AKR1A1 antibody (ab125878) at 1/1000 dilution

    Lane 1 : A549 whole cell lysate
    Lane 2 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 37 kDa

Anti-AKR1A1 antibody (ab125878)参考文献

ab125878 has not yet been referenced specifically in any publications.

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