概述

  • 产品名称Anti-AKAP13抗体
    参阅全部 AKAP13 一抗
  • 描述
    小鼠单克隆抗体to AKAP13
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1-111 of Human AKAP13

性能

应用

Our Abpromise guarantee covers the use of ab56916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element-specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Isoform 6 stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions.
    • 组织特异性Isoform 3 and isoform 6 are found in hematopoietic cells, skeletal muscle, lung, heart, estrogen-responsive reproductive tissues, including breast ductal epithelium. Also found in testis and breast cancer cell lines. Isoform 6 is not found in brain, placenta, liver, pancreas or kidney. Isoform 7 is expressed in myeloid and lymphoid lineages, a variety of epithelial tissues and skeletal muscle. Isoform 2 is predominantly found in the heart and at lower levels in the lung, placenta, kidney, pancreas, skeletal muscle and liver.
    • 序列相似性Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
    • 结构域Both the DH and PH domains are required for transforming activity.
    • 细胞定位Cytoplasm; Cytoplasm. Nucleus and Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A kinase (PRKA) anchor protein 13 antibody
      • A kinase anchor protein 13 antibody
      • A kinase anchoring protein antibody
      • A-kinase anchor protein 13 antibody
      • AKAP 13 antibody
      • AKAP Lbc antibody
      • AKAP-13 antibody
      • AKAP-Lbc antibody
      • AKAP13 antibody
      • AKP13_HUMAN antibody
      • ARHGEF13 antibody
      • Breast cancer nuclear receptor binding auxiliary protein antibody
      • Breast cancer nuclear receptor-binding auxiliary protein antibody
      • BRX antibody
      • c lbc antibody
      • FLJ11952 antibody
      • FLJ43341 antibody
      • Guanine nucleotide exchange factor Lbc antibody
      • HA 3 antibody
      • HA3 antibody
      • Ht 31 antibody
      • Ht31 antibody
      • Human thyroid anchoring protein 31 antibody
      • Human thyroid-anchoring protein 31 antibody
      • LBC antibody
      • LBC oncogene antibody
      • Lymphoid blast crisis oncogene antibody
      • Non oncogenic Rho GTPase specific GTP exchange factor antibody
      • Non-oncogenic Rho GTPase-specific GTP exchange factor antibody
      • p47 antibody
      • Protein kinase A anchoring protein 13 antibody
      • Protein kinase A-anchoring protein 13 antibody
      • PROTO LB antibody
      • PROTO LBC antibody
      see all

    Anti-AKAP13 antibody 图像

    • Anti-AKAP13 antibody (ab56916) at 5 µg/ml + 0.2 µg/lane of partial recombinant AKAP13 protein with a tag

      Secondary
      Goat anti mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 308 kDa
      Observed band size : 38 kDa (why is the actual band size different from the predicted?)

    Anti-AKAP13 antibody (ab56916)参考文献

    ab56916 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56916.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"