参阅全部 AKAP12 一抗
- 特异性ab118365 is expected to recognize isoform 1 (NP_005091.2) only.
SPDTNGPKLTEEGD with a Cysteine residue linker, corresponding to internal sequence amino acids 1645-1658 of Mouse AKAP12 (NP_112462.1).
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- 存储溶液pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
- 纯度Immunogen affinity purified
- 纯化说明ab118365 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
应用说明Is unsuitable for WB.
- 功能Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
- 组织特异性Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells.
- 序列相似性Contains 3 AKAP domains.
- 结构域Polybasic regions located between residues 266 and 557 are involved in binding PKC.
- 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
- 细胞定位Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. May be part of the cortical cytoskeleton.
Information by UniProt
- A kinase (PRKA) anchor protein (gravin) 12 antibody
- A kinase Anchor Protein 12 antibody
- A kinase anchor protein 250kDa antibody
Anti-AKAP12 antibody (ab118365)参考文献
has not yet been referenced specifically in any publications.
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