概述

  • 产品名称Anti-AIPL1抗体
    参阅全部 AIPL1 一抗
  • 描述
    兔多克隆抗体to AIPL1
  • 经测试应用适用于: WB, ELISA, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A 17 amino acid synthetic peptide near the carboxy terminus of human AIPL1 (NP_055151).

  • 阳性对照
    • Human brain tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab79039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能May be important in protein trafficking and/or protein folding and stabilization.
  • 组织特异性Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
  • 疾病相关Defects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
  • 序列相似性Contains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A930007I01Rik antibody
    • Aipl1 antibody
    • AIPL1_HUMAN antibody
    • AIPL2 antibody
    • Aryl hydrocarbon interacting protein like 1 antibody
    • Aryl hydrocarbon receptor interacting protein like 1 antibody
    • Aryl-hydrocarbon-interacting protein-like 1 antibody
    • LCA4 antibody
    • MGC25485 antibody
    • OTTHUMP00000128207 antibody
    • OTTMUSP00000006382 antibody
    • RP23-401C17.1 antibody
    see all

Anti-AIPL1 antibody 图像

  • Immunofluorescence of AIPL1 in Human brain tissue with ab79039 at 20 ug/mL.

  • Immunohistochemistry of Human brain tisue using ab79039 at 2.5 μg/ml.

  • Lane 1 : Anti-AIPL1 antibody (ab79039) at 1 µg/ml
    Lane 2 : Anti-AIPL1 antibody (ab79039) at 2 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 44 kDa
    Observed band size : 36 kDa (why is the actual band size different from the predicted?)

Anti-AIPL1 antibody (ab79039)参考文献

ab79039 has not yet been referenced specifically in any publications.

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