Synthetic peptide, corresponding to a sequence within amino acids 1393-1455 of Human AIP1 (NP_036433).
A431, H1299, HeLa, HepG2 and Raji cells
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 1X PBS, pH 7.0
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 159 kDa.
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.
Specifically expressed in brain.
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain. Contains 6 PDZ (DHR) domains. Contains 2 WW domains.
Cell junction > synapse > synaptosome. Cell membrane. Membrane-associated in synaptosomes.
Information by UniProt
Activin receptor interacting protein 1 antibody
Anti-AIP1 antibody (ab97343)参考文献
has not yet been referenced specifically in any publications.
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