概述

  • 产品名称Anti-AIMP3/p18抗体
    参阅全部 AIMP3/p18 一抗
  • 描述
    兔多克隆抗体to AIMP3/p18
  • 特异性ab31543 reacts specifically with 21kDa p18 and immunoprecipitates with ATM/ATR
  • 经测试应用适用于: WB, IP, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Native full length recombinant human p18

  • 阳性对照
    • HEK293 cell, U2OS cell and Hela cell

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Sodium Azide
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab31543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/8000. Detects a band of approximately 21 kDa (predicted molecular weight: 18 kDa).
IP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

靶标

  • 功能Positive modulator of ATM response to DNA damage.
  • 组织特异性Down-regulated in various cancer tissues.
  • 序列相似性Contains 1 GST C-terminal domain.
  • 细胞定位Cytoplasm. Nucleus. Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AIMP 3 antibody
    • AIMP3 antibody
    • Aminoacyl tRNA synthetase complex interacting multifunctional protein 3 antibody
    • Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 antibody
    • ARS interacting multifunctional protein 3 antibody
    • EEF1E1 antibody
    • Elongation factor p18 antibody
    • Eukaryotic translation elongation factor 1 epsilon 1 antibody
    • Eukaryotic translation elongation factor 1 epsilon-1 antibody
    • Homolog of rat elongation factor p18 antibody
    • MCA3_HUMAN antibody
    • Multisynthase complex auxiliary component p18 antibody
    • Multisynthetase complex auxiliary component p18 antibody
    • p18 antibody
    • p18 component of aminoacyl tRNA synthetase complex antibody
    see all

Anti-AIMP3/p18 antibody 图像

  • Anti-AIMP3/p18 antibody (ab31543) at 1/20000 dilution + HEK293 cell line

    Predicted band size : 18 kDa
    Observed band size : 21 kDa (why is the actual band size different from the predicted?)
  • Anti-AIMP3/p18 antibody (ab31543) at 1/8000 dilution + whole cell lysate prepared from HEK293 cells at 50 µg/ml

    Secondary
    Goat anti-rabbit IgG (H+L) at 1/10000 dilution

    Predicted band size : 18 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

Anti-AIMP3/p18 antibody (ab31543)参考文献

This product has been referenced in:
  • Gulati P  et al. Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proc Natl Acad Sci U S A 110:2557-62 (2013). WB ; Mouse . Read more (PubMed: 23359686) »
  • Du Y  et al. Elevation of Highly Up-regulated in Liver Cancer (HULC) by Hepatitis B Virus X Protein Promotes Hepatoma Cell Proliferation via Down-regulating p18. J Biol Chem 287:26302-11 (2012). WB ; Human . Read more (PubMed: 22685290) »

See all 4 Publications for this product

Product Wall

Thank you for contacting us and reporting the problems observed with your current batch of ab31543. As discussed over the phone, it may be that unfortunately you have received a faulty batch. I have organised for a free of charge replacement to be...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"