Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
Synthetic peptide (EGFSDRIVLC TLDRHLPYDR PKLSKSLDTQ PEQLALRPKE FFRAYGIEVL) corresponding to a region within internal sequence amino acids 216-265 of human AIFM3 (NP_653305).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Immunogen affinity purified
Purified by peptide affinity chromatography method.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 67 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
||Use at an assay dependent concentration.
Titre using peptide based assay: 1/312500.
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain.
The Rieske domain induces apoptosis.
Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
Information by UniProt
- AIFL antibody
- Aifm3 antibody
- AIFM3_HUMAN antibody
Anti-AIFM3 antibody (ab83791)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"